Carnegie Mellon University

 Andreas Pfenning

Associate Professor, Computational Biology Department


Gates Hillman Center Room 7711
Computational Biology Department, SCS
Carnegie Mellon University
5000 Forbes Avenue
Pittsburgh, PA 15213

Email   Lab Website

Administrative Assistant: Shelly Ossman


Over the last several decades, the genetic revolution has showed us that much of human biology, even complex behavior, is encoded in our genome. Most of the variation in genome sequence that influences neurological disease predisposition and behavioral ability occurs in the vast regulatory regions between genes. The goal of the Pfenning laboratory is to build a set of computational and experimental genomic tools to study how sequence differences in those regions influence neurons, neural circuits, disease predisposition, and behavior. By understanding the genetic mechanisms underlying neural function, we seek to uncover the cell type-specific basis of Alzheimer’s disease and addiction, as well as gain insights into how speech production ability evolved in the human lineage.

Lab Members

 Ashley Brown

Lab Manager

 Lahari Gadey

Lab Technician

 Vijay Cherupally

Research Associate

 Heather Harper Sestili

Research Programmer

 Ziheng (Calvin) Chen

Ph.D. Student

 Irene Kaplow

Lane Fellow

  Rajee Ganesan

Ph.D. Student

 Mike Leone

Ph.D. Student

 BaDoi Phan

MSTP Student

 Chai Srinivasan

Ph.D. Student

 Cathy Su

Ph.D Student

 Spencer Gibson

Masters Student

placeholder-image.png Tianyu Lu

Masters Student

 Amy Zhu

Masters Student

 Arian Raje

Undergraduate Student

  Ruby Redlich

Undergraduate Student

 Daniel Schaffer

Undergraduate Student

 Amy Stephen

Undergraduate Student

 Andrew Wang

Undergraduate Student